Correlation between auditory brainstem response and hearing prognosis in idiopathic sudden sensorineural hearing loss patients

Publication date: Available online 31 January 2017
Source:Auris Nasus Larynx
Author(s): Hung-Che Lin, Yu-Ching Chou, Chih-Hung Wang, Li-Wen Hung, Cheng-Ping Shih, Bor-Hwang Kang, Wen-Ying Yeh, Hsin-Chien Chen
ObjectiveTo investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).MethodsPatients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed.ResultsOne hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group.ConclusionsThere was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.



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