Natural Killer T-Cell Lymphoma of the Orbit: An Evidence-Based Approach.

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Natural Killer T-Cell Lymphoma of the Orbit: An Evidence-Based Approach.

Semin Ophthalmol. 2017;32(1):116-124

Authors: Jiménez-Pérez JC, Yoon MK

Abstract
Natural killer T-cell lymphoma (NKTCL) is a rare and aggressive condition with a high mortality rate. It is most commonly seen in the nasal sinuses, generally affecting the orbit by direct extension. Primary orbital NKTCL is even more rare, with only a few published cases with occasional secondary nasal involvement. This malignancy can present as a "masquerade syndrome," delaying proper diagnosis and treatment. Biopsy is required for diagnosis, which shows specific histopathological characteristics. Radiation and chemotherapy are the mainstay of treatment. Newer chemotherapies show improved prognosis.

PMID: 27740876 [PubMed - indexed for MEDLINE]

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