Τρίτη 14 Φεβρουαρίου 2017

Sphenoid sinus carcinoid tumour causing ectopic ACTH syndrome

Sphenoid sinus carcinoid tumour causing ectopic ACTH syndrome: A thirty-eight year old patient presented with a gradual increase in weight and Cushingoid facies of two years duration. He also had orbital congestion, with puffy eyelids and corkscrew conjunctival vessels, associated with painful eye movements. An endocrine evaluation revealed raised cortisol and ACTH. Head imaging was performed which showed an enhancing tumour arising from the sphenoid sinus, with osseous erosion of the sphenoid sinus, extending to the nasopharynx, sellar and a small amount extending intracranially.




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