WHO Response to Disease Outbreaks in Liberia: Lessons learned from the 2014 - 2015 Ebola Virus Disease OutbreakThis special issue of the Pan African Medical Journal documents the successful application of lesson learnt from response to the Ebola virus disease outbreak in Liberia and identifies some best practices that could be applied to other disease prevention, control and elimination programmes with similar success. The papers, written by those who were actively engaged in response to epidemics...
Case Studies for Public Health in the Eastern Mediterranean Region - 2019The Eastern Mediterranean Public Health Network (EMPHNET) helped to launch and establish several Field Epidemiology Training Programs (FETPs) in the Eastern Mediterranean Region (EMR). EMPHNET continues to provide ongoing technical and programmatic support for these program in an effort to assist countries to strengthen their public health workforce. The FETP programs in our region have relied, right now, on fewer local specific...
Tumor surgery, the microbiome, and anaphylaxis Timothy L. Smith MD, MPH, FACS First published: 07...
Tumor surgery, the microbiome, and anaphylaxisTimothy L. Smith MD, MPH, FACSFirst published: 07 June 2019 https://doi.org/10.1002/alr.22358
Outcomes of sinonasal inverted papilloma resection by surgical approach: an updated systematic review and meta‐analysisRui Peng MD Andrew Thamboo MD Garret Choby MD Yifei Ma MS Bing Zhou MD, PhD Peter H. Hwang MDFirst published: 12 February 2019 https://doi.org/10.1002/alr.22305 Cited by: 1Potential conflict of interest: None provided.Presented at the American Rhinologic Society Annual Meeting on October 5‐6, 2018, in Atlanta, GA.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundSelecting...
The difference in nasal bacterial microbiome diversity between chronic rhinosinusitis patients with polyps and a control populationWeigang Gan MD Fengjuan Yang MM Yiping Tang MM Danmei Zhou MM Di Qing MM Juanjuan Hu MD Shixi Liu MD Feng Liu MD Juan Meng MDFirst published: 05 February 2019 https://doi.org/10.1002/alr.22297 Cited by: 2The first 2 authors, W.G. and F.Y., contributed equally to this work.Funding sources for the study: National Science Fund of China (81300815 to J.M., and 81570310000...
Symptom importance, patient expectations, and satisfaction in chronic rhinosinusitisJose L. Mattos MD, MPH Luke Rudmik MD, MSc Rodney J. Schlosser MD Timothy L. Smith MD, MPH Jess C. Mace MPH Jeremiah Alt MD, PhD Zachary M. Soler MD, MScFirst published: 12 February 2019 https://doi.org/10.1002/alr.22309Funding sources for the study: National Institute on Deafness and Other Communication Disorders, National Institutes of Health (R01 DC005805 [PI: T.L.S./Z.M.S.] to J.A.A., R.J.S., J.C.M., T.L.S.,...
Does bilateral inferior turbinate reduction affect long‐term quality‐of‐life outcomes in patients undergoing endoscopic sinus surgery?George A. Scangas MD Benjamin S. Bleier MD Qasim Husain MD Eric H. Holbrook MD Stacey T. Gray MD Ralph Metson MDFirst published: 31 January 2019 https://doi.org/10.1002/alr.22300Potential conflict of interest: None provided.Presented orally at the Annual ARS Meeting on October 5‐6, 2018, in Atlanta, GA.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundThe...
Epidemiology and trends of anaphylaxis in the United States, 2004‐2016Mohamad R. Chaaban MD, MBA, MSCR Zachary Warren BS Jacques G. Baillargeon PhD Gwen Baillargeon MS Vicente Resto MD, PhD Yong‐Fang Kuo PhDFirst published: 04 February 2019 https://doi.org/10.1002/alr.22293 Cited by: 1Potential conflicts of interest: J.B.: AbbVie, Auxilium, Endo, and GlaxoSmithKline, consultant.Presented at the American Academy of Otolaryngic Allergy Annual Meeting, Philadelphia, PA, in September 2018.Read the...
An analysis of factors associated with compliance and dropout of sublingual immunotherapy on Japanese cedar pollinosis patientsTakahiro Imanaka MSc Izumi Sato PhD Yohei Kawasaki PhD Yuji Kanazawa MD, PhD Koji Kawakami MD, PhDFirst published: 05 February 2019 https://doi.org/10.1002/alr.22308Potential conflicts of interest: None provided.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundSublingual immunotherapy (SLIT) is safe and effective but compliance is problematic. In this study we evaluated...
Sensitivity, specificity, and predictive value of oral mucosal brush biopsy for the diagnosis of peanut allergyYu Ting He BS William R. Reisacher MD, FACS FAAOAFirst published: 05 February 2019 https://doi.org/10.1002/alr.22302Funding sources for the study: American Academy of Otolaryngic Allergy Foundation (AAOAF).Potential conflict of interest: W.R.R. is the inventor on Patent US 8,993,347 B2.Presented at the American Academy of Otolaryngic Allergy (AAOA) Annual Scientific Meeting on September...
Herbal dry extract BNO 1011 improves clinical and mucociliary parameters in a rabbit model of chronic rhinosinusitisDo‐Yeon Cho MD Daniel Skinner BS Calvin Mackey BS Harold B Lampkin BS Jeffrey Brent Elder BS Dong Jin Lim PhD Shaoyan Zhang PhD Justin McCormick MD … See all authorsFirst published: 18 January 2019 https://doi.org/10.1002/alr.22290Funding sources for the study: Bionorica SE (Neumarkt, Germany) (to D.Y.C. and B.A.W.); NIH (National Heart, Lung, and Blood Institute [NHLBI] 1 R01...
Protective effects of α‐lipoic acid on cultured human nasal fibroblasts exposed to urban particulate matterDong Chang Lee MD, PhD Hyunsu Choi MS Jeong‐Min Oh MS Do Hee Lee MD, a Bachelor of Medicine (B.M.) Sung Won Kim MD, PhD Soo Whan Kim MD, PhD Byung Guk Kim MD, PhD … See all authorsFirst published: 13 February 2019 https://doi.org/10.1002/alr.22296Funding sources for the study: This research was supported by the Basic Science Research Program through the National Research Foundation of...
Effects of azathioprine and its metabolites on inflammatory cytokines in human nasal polyp organ culturesNam‐Kyung Yeo MD, PhD Woo Joo Park MD Daeo‐Woon Eom MD, PhD Mi Young Oh MSc Ji Hwan Lee MScFirst published: 12 February 2019 https://doi.org/10.1002/alr.22303Funding sources for the study: Basic Research Program through Gangneung Asan Hospital Medical Institute funded by the Asan Foundation (2016‐12‐011‐002); National Research Foundation of Korea (NRF) grant funded by the Korea Government...
Survivin facilitates T‐helper 2–biased inflammation in the airwayJin‐Mei Xue MD, PhD Mei‐Zhen Zhao PhD Fei Ma MD, PhD Shan‐Shan Li MSc Li‐Hua Mo MSc Xian‐Hai Zeng MD Yong‐Jin Wu MD Jiang‐Qi Liu MD Tian‐Yong Hu MSc Rui‐Di Xie MD … See all authorsFirst published: 04 February 2019 https://doi.org/10.1002/alr.22301Funding sources for the study: National "13th‐5" Key Programme; Precision Medicine Research Project (2016YFC0905802 and 2016YFC0903700); Guangdong Provincial Scientific Technological...
The impact of race and insurance status on baseline histopathology profile in patients with chronic rhinosinusitisHannah N. Kuhar BA Ashwin Ganti BA Michael Eggerstedt MD Mahboobeh Mahdavinia MD, PhD Paolo Gattuso MD Ritu Ghai MD Pete S. Batra MD, FACS Bobby A. Tajudeen MDFirst published: 12 February 2019 https://doi.org/10.1002/alr.22295Funding sources for the study: Cohn scholarship program from Rush University (to M.M.); Medtronic (research grant to P.S.B.).Potential conflicts of interest:...
Outcomes and imaging findings of respiratory epithelial adenomatoid hamartoma: a systematic reviewChetan Safi MD Carol Li MD Abtin Tabaee MD Rohan Ramakrishna MD Charles A. Riley MDFirst published: 18 January 2019 https://doi.org/10.1002/alr.22298Potential conflict of interest: None provided.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundRespiratory epithelial adenomatoid hamartoma (REAH) is a recently classified histopathologic diagnosis often identified incidentally following endoscopic...
Use of intranasal submucosal fillers as a transient implant to alter upper airway aerodynamics: implications for the assessment of empty nose syndromeNicole A. Borchard BA Sachi S. Dholakia BS Carol H. Yan MD David Zarabanda MD Andrew Thamboo MD, MHSc Jayakar V. Nayak MD, PhDFirst published: 04 February 2019 https://doi.org/10.1002/alr.22299Potential conflict of interest: None provided.Presented orally at the Annual ARS Meeting on October 5‐6, 2018, in Atlanta, GA.Read the full textePDFPDFTOOLS...
Rates of symptomatology are lower in recurrent sinonasal malignancy than in other recurrent cancers of the head and neck: a multi‐institutional studyAlan D. Workman MD, MTR Nathalia Velasquez MD Nayel I. Khan MD Nicole A. Borchard BS Edward C. Kuan MD, MBA James N. Palmer MD Eric W. Wang MD Zara M. Patel MD Nithin D. Adappa MDFirst published: 15 February 2019 https://doi.org/10.1002/alr.22310Potential conflicts of interest: None provided.Presented orally at the Fall Meeting of the American...
Creation and validation of three‐dimensional printed models for basic nasal endoscopic trainingChen Zhuo MD Lyu Lei PhD Zhao Yulin MD Liu Wentao PhD Wu Shuangxia MD Wang Chao PhD Zhang Yaqian MD Huang Shuman MD Dong Dong MDFirst published: 12 February 2019 https://doi.org/10.1002/alr.22306C.Z., L.L., and Z.Y. contributed equally to this work.Funding sources for the study: Youth Fund Program of the First Affiliated Hospital of Zhengzhou University of China (20151104).Potential conflict of interest:...
Microwave ablation for the treatment of arterial epistaxis: "how I do it"Zheng‐Cai Lou MD Yihan Dong MD Zi‐Han Lou MBBSFirst published: 31 January 2019 https://doi.org/10.1002/alr.22304Z.C.L. and Y.D. contributed equally to this work and are co‐first authors.Potential conflict of interest: None.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundArterial epistaxis is commonly seen in the rhinology clinic and can have a significant impact on quality of life. Previous studies have explored various...
Corporate social responsibility in community development and sustainability: Rourkela Steel Plant, a unit of SAIL, IndiaAbstractAn attempt is made in this article to explore and build knowledge on the corporate social responsibility (CSR) performances for community development and sustainability in the context of Rourkela Steel Plant of Steel Authority of India in Odisha, particularly in the wake of Companies Act, section 135, 2013. The paper looks at the conduct of CSR transitional strategy if any...
Ethical management and leadership: a conceptual paper and Korean example Abstract Business ethics...
Ethical management and leadership: a conceptual paper and Korean exampleAbstractBusiness ethics have become an important topic globally for both policy-makers and businesses. This paper first discusses the conceptual framework for business ethics followed by ethical management (EM) and corporate social responsibility (CSR) as well as relevant theories. Within this conceptual framework, Korea is used as a country context as to the development of EM and CSR. An important example of an ethical scandal...
Lippincott Journals Monthly Update: Otolaryngology Case Studies Comparing Learning Profiles and Response to Instruction in Autism Spectrum Disorder and Oral and Written Language Learning Disability at Transition to High SchoolTopics In Language Disorders This study investigated literacy learning in students with specific kinds of language challenges at a specific stage of schooling—transition to high school—when the language requirements of the curriculum can be especially challenging. For this exploratory...
Effects of perceived organizational CSR value and employee moral identity on job satisfaction: a study of business organizations in ThailandAbstractResearch has shown that corporate social responsibility (CSR) can have a positive impact on the firm's reputation and financial performance. Moreover, CSR activities can have a positive impact on employees' workplace experience. Consistent with past research, we argue that perceived organizational CSR value can have a positive impact on job satisfaction....
May I be a sacrifice for my grandchildren—transgenerational transmission and women's narratives of the Yezidi fermanAbstractThis paper addresses the (post)-memories of the generations of offspring of survivors of the genocidal processes in the Ottoman Empire during World War I. About 12,000 Yezidis managed to flee to Armenia and establish a diasporic community. Based on ethnographic fieldwork within this community, including interviews with members of subsequent generations, this article focuses...
Gender and memory in the Middle East: on transgenerational transmission and agencyColonial incarceration: Palestinians on permanent lock downLullabies and the memory of pain: Armenian women's remembrance of the past in TurkeyMay I be a sacrifice for my grandchildren—transgenerational transmission and women's narratives of the Yezidi fermanAbstractThis paper addresses the (post)-memories of the generations of offspring of survivors of the genocidal processes in the Ottoman Empire during World War...
Assessing temporary foreign worker programs through the prism of Canada's Seasonal Agricultural Worker Program: can they be reformed or should they be eliminated?AbstractThis article assesses Temporary Foreign Worker Programs (TFWPs) through the prism of Canada's Seasonal Agriculture Worker Program (SAWP), often represented as a model because of the many rights granted workers and the multiple forms of protection put in place to protect those rights. A careful study of the extant anthropological...
Migration or immigration? Commentary on Leigh Binford's articleAbstractIn this commentary of Leigh Binford's article, proposing the elimination of Canada's Seasonal Agricultural Workers Program (SAWP), I will first offer a brief overview of why advanced capitalist countries like Canada must rely on migrant or immigrant workers to sustain economic growth. I will then sum up Binford's main arguments and analysis. Finally, I will address the question of elimination and replacement of the SAWP based...
Environmental impact of combustion of ethanolic biodiesel/diesel blends from several feedstocks on the gas emission levels in the atmosphereAbstractThe aim of this work was to evaluate simultaneously the effect of produced ethanolic biodiesel from several feedstocks (soybean, crambe, macaw, sunflower, and waste cooking oil) and engine operational conditions (low and high engine speed) during combustion of biodiesel/diesel blends on the N2O, NOx, NO, CO2, and CO emission levels in the atmosphere....
Mineralogical, chemical and leaching characteristics of ashes from residential biomass combustionAbstractFour types of pellets and three agro-fuels were chemically characterised and burned in a pellet stove. To assess the influence of the material composing the firebox and the combustion efficiency of distinct biomass heating devices in the composition of the bottom ashes, three of the pellets were also burned in a conventional woodstove and in a fireplace. Ashes were analysed for their C, H and...
Growth, accumulation and uptake of Eichhornia crassipes exposed to high cadmium concentrationsAbstractA greenhouse experiment was performed to evaluate the growth, accumulation, and uptake rate of Eichhornia crassipes subject to high cadmium concentrations. Three doses of Cd were added to polluted river water (1, 5, and 10 mg Cd/L), and polluted water with basal Cd concentration (0.070 mg/L) was used as a control. The experiment lasted for 7 days. Signs of stress and toxicity were visible in all...
The role of financial sector in energy demand and climate changes: evidence from the developed and developing countriesAbstractThis paper searches the role of financial sector development in energy sector and therefore in climate changes in the case of developing and developed countries. Panel data ranging from 1960 to 2014 on an annual basis has been selected from 176 countries. Results suggest that carbon dioxide emissions in developed and developing countries are in long-term equilibrium relationship...
Characteristics of vegetable crop cultivation and nutrient releasing with struvite as a slow-release fertilizerAbstractStruvite precipitation is an effective method to remove and recover ammonia and phosphate from livestock wastewater. Struvite has properties similar to those of the traditional ammonium-phosphate fertilizer, which does not burn the roots owing to its slow-release characteristics. Struvite is an effective fertilizer as its nutrient-releasing rate is very slow. But the release rate...
Renewable and non-renewable energy use and its relationship with economic growth in MyanmarAbstractThis study aims to investigate the dynamic relationship between renewable and non-renewable energies, CO2 intensity and economic growth for the period of 1990–2016 using a case study of Myanmar. Autoregressive distributed lag, dynamic OLS, fully modified OLS and Gregory–Hansen co-integration are applied to analyse a time series dataset over the specified time period. The analysis shows that total energy...
Rural household preferences for cleaner energy sources in PakistanAbstractDependence of rural population on traditional fuel sources namely biomass has increased because of easy accessibility and affordability. The use of biomass fuels results in many environmental and health-related hazards. Rural households have little awareness about the ill effects of using biomass energy sources. This study investigated the patterns of rural household energy use and identified the role of information on the...
Occurrence of polycyclic aromatic hydrocarbons (PAHs) in air and soil surrounding a coal-fired thermal power plant in the south-west coast of IndiaAbstractThis investigation focused on the potential sources of polycyclic aromatic hydrocarbons (PAHs) in different matrices and their temporal variations surrounding a coal-fired thermal power plant in India. Samples were collected in different seasons for 1 year. Gas chromatography-mass spectroscopy (GC-MS) was used to perform the measurement of 16 priority...
Potential dietary factors for reducing lead burden of Chinese preschool childrenAbstractDietary approaches to treat children's low lead exposure are implemented routinely in China, while evidence for the effect could not be provided until now. The aim of this study was to examine the relationship between diets including nutrition supplementation and blood lead level of preschool children of China. In total, 17,859 preschool children from 14 cities were recruited, and their social-demography, living...
Arsenic contamination in Kolkata metropolitan city: perspective of transportation of agricultural products from arsenic-endemic areasAbstractArsenic exposure route for humans is through the drinking of contaminated water and intake of arsenic-contaminated foods, particularly in arsenic-exposed areas of Bengal delta. Transport of the arsenic-contaminated crops and vegetables grown using arsenic-contaminated groundwater and soil in arsenic-exposed areas to the uncontaminated sites and consequent dietary...
Environmental impact of combustion of ethanolic biodiesel/diesel blends from several feedstocks on the gas emission levels in the atmosphereAbstractThe aim of this work was to evaluate simultaneously the effect of produced ethanolic biodiesel from several feedstocks (soybean, crambe, macaw, sunflower, and waste cooking oil) and engine operational conditions (low and high engine speed) during combustion of biodiesel/diesel blends on the N2O, NOx, NO, CO2, and CO emission levels in the atmosphere....
LOS PEPTIDOS ANTIMICROBIANOS Y SUS BENEFICIOS EN EL TRATAMIENTO DE LAS ULCERAS DE PIE DIABETICO Resumen La úlcera de pie diabético es una de las complicaciones más importantes de la diabetes mellitus tipo 2; de hecho, hasta un 30% de los pacientes diabéticos presentan esta complicación. En los últimos años se han implementado nuevas terapias para tratar de promover la rápida cicatrización de este tipo de úlceras, enfocándose en la terapia antibiótica, el restablecimiento de la vascularización, la...
Acid Suppression Therapy and Symptom Improvement (or Lack Thereof) in ChildrenMary Boruta, Richard Boruta, Jennifer LiArticle Info & Metrics Comments Download PDFAbbreviations: GER — gastroesophageal refluxH2RA — histamine H2-receptor antagonistHR — hazard ratioPPI — proton pump inhibitorAcid suppression therapy, in the form of histamine H2-receptor antagonists (H2RAs) and proton pump inhibitors (PPIs), is a common treatment in pediatrics for management of gastroesophageal reflux (GER). Symptoms...
Early Acid Suppression Therapy Exposure and Fracture in Young ChildrenLaura Malchodi, Kari Wagner, Apryl Susi, Gregory Gorman, Elizabeth Hisle-GormanArticle Figures & Data Supplemental Info & Metrics Comments Download PDFPediatricsJune 2019ArticleAbstractBACKGROUND: Acid suppression therapy (AST), including proton pump inhibitors (PPIs) and histamine H2-receptor antagonists (H2RAs), is frequently prescribed to treat symptomatic gastroesophageal reflux in otherwise healthy infants. PPI...
Cultivation and characterization of the bacterial assemblage of epsomic Basque Lake, BCAbstractAthalassohaline waters that are rich in divalent ions are good analogues for the chemical environments of Mars and the ocean worlds. Sulfate salts, along with chlorides, are important in Mars regolith with Ca, Fe, Mg, and Na counterions. Certain lakes in the Pacific Northwest are saturated with MgSO4 as epsomite. Here we report on the microbial community of Basque Lake, BC, a group of playas that is saturated...
Halalkalicoccus subterraneus sp. nov., an extremely halophilic archaeon isolated from a subterranean halite depositAbstractAn extremely halophilic archaeon, designated strain GSM28T, was isolated from a subterranean halite deposit in a Yunnan salt mine, China. Cells of the strain were observed to be cocci, non-motile and Gram-variable, and to require at least 15% (w/v) NaCl for growth (optimum 20%). Growth was found to occur in the ranges of 20–45 °C (optimum 42 °C) and pH 6.0–8.5 (optimum 7.5)....
Ulvibacterium marinum gen. nov., sp. nov., a novel marine bacterium of the family Flavobacteriaceae , isolated from a culture of the green alga Ulva proliferaAbstractA Gram-stain negative, aerobic, rod-shaped, and non-motile bacterium, designated strain CCMM003T, was isolated from a culture of the green alga Ulva prolifera. Phylogenetic analysis based on 16S rRNA gene sequences showed that strain CCMM003T belongs to the family Flavobacteriaceae and exhibits a close relationship to Pseudozobellia...
Neisseria chenwenguii sp. nov. isolated from the rectal contents of a plateau pika ( Ochotona curzoniae )AbstractTwo Gram-stain negative, catalase positive, coccus shaped bacteria, designated 10023T and 10010, were isolated from the rectal contents of a plateau pika (Ochotona curzoniae) in Qinghai–Tibet Plateau, China. Based on 16S rRNA gene sequence analysis, phylogenetic trees showed that these two isolates (10023T, 10010) group with members of the genus Neisseria. Additionally, these two isolates...
Production of a novel killer toxin from Saccharomyces eubayanus using agro-industrial waste and its application against wine spoilage yeastsAbstractThe juicing industry generates large amounts of waste that mostly lack commercial value and, in the absence of waste treatment policies, produces environmental pollution. Also, microbiological spoilage is a major concern in the wine industry and control tools are limited. Taking these challenges into account, agro-industrial waste coming from ultrafiltrated...
Transcription factor CgAzf1 regulates melanin production, conidial development and infection in Colletotrichum gloeosporioidesAbstractRubber anthracnose caused by Colletotrichum gloeosporioides leads to huge economic loss in the natural rubber industry every year. Conidia of C. gloeosporioides are a major infection source but little is known about molecular mechanisms underlying conidial development and infection. In this study, the C. gloeosporioide C2H2 zinc-finger protein transcription factor...
Hymenobacter persicinus sp. nov., a novel member of the family HymenobacteraceaeAbstractA bacterial strain, 1-3-3-3T, was isolated from a soil sample collected in Jeollabuk-do province, South Korea. Cells were observed to be Gram-stain negative, short rod-shaped and colonies to be red-pink in colour. Analysis of 16S rRNA gene sequences identified this strain as a member of the genus Hymenobacter in the family Hymenobacteraceae, with high levels of 16S rRNA sequence similarity with Hymenobacter algoricola VUG-A23aT(98.0%), Hymenobacter...
Detection and virulence potential of a phospholipase D-negative Corynebacterium ulcerans from a concurrent diphtheria and infectious mononucleosis caseAbstractDiphtheria by Corynebacterium ulcerans is increasingly occurring in children, adolescents and adults. In addition to diphtheria toxin (DT), phospholipase D (PLD) is considered a virulence factor of C. ulcerans. In the present study, a first case of concurrent diphtheria by a PLD-negative C. ulcerans and infectious mononucleosis (IM) was verified....
Tellurirhabdus rosea gen. nov., sp. nov., a new member of the family Cytophagaceae isolated from soil in South KoreaAbstractStrain U15T, rod-shaped, catalase and oxidase positive, non-motile, hot pink pigmented, Gram-negative bacterium, was isolated from soil of Udo port, Udo Island, South Korea. Growth was observed at 10–48 °C, pH 6–11, and 0% (w/v) NaCl. Optimum growth conditions are 30–40 °C, pH 7–10, and 0% (w/v) NaCl. Phylogenetic analysis based on 16S rRNA sequences showed that strain U15T forms...
Cohnella candidum sp. nov., radiation-resistant bacterium from soilAbstractA Gram-stain positive, endospore-forming, circular, convex, cream colored, designated strain 18JY8-7T, was isolated from soil collected in Jeju Island, South Korea. Phylogenetic analysis using 16S rRNA gene sequences showed that strain 18JY8-7T formed a distinct lineage within the family Paenibacillaceae (order Bacillales, class Bacilli), and is closely related to Cohnella rhizosphaerae (96.1%, sequence similarity) and Cohnella...
Cohnella candidum sp. nov., radiation-resistant bacterium from soilAbstractA Gram-stain positive, endospore-forming, circular, convex, cream colored, designated strain 18JY8-7T, was isolated from soil collected in Jeju Island, South Korea. Phylogenetic analysis using 16S rRNA gene sequences showed that strain 18JY8-7T formed a distinct lineage within the family Paenibacillaceae (order Bacillales, class Bacilli), and is closely related to Cohnella rhizosphaerae (96.1%, sequence similarity) and Cohnella...
ARTÍCULOS DE FUENTES SELECCIONADASLos artículos de fuentes seleccionadas son resumidos en castellano por el Comité de Redacción Científica de SIIC.Beatriz Rodríguez AlonsoPAPEL DEL ESPECIALISTA EN HIGIENE Y EPIDEMIOLOGÍA EN LOS ESTUDIOS EXPERIMENTALESPara el desarrollo de los ensayos clínicos se requiere de un equipo de investigación multidisciplinaria, integrado por especialistas y técnicos que deben garantizar el cumplimiento de las normas de buena práctica clínica y, por ende, resultados confiables...
Neuroimaging assessment in Down syndrome: a pictorial reviewAbstractDown syndrome (DS), or trisomy 21, is the leading genetic cause of intellectual incapacity worldwide, with a reported incidence of about 1 in 1,000 to 1 in 1,100 live births. Besides the several commonly known physical features characteristic of this syndrome present at birth, DS may additionally affect every organ system. In addition, despite the large number of published papers concerning this syndrome, there is scarce literature...
Cryoablation and immunotherapy: an overview of evidence on its synergyAbstractCancer cells can escape the immune system by different mechanisms. The evasion of cancer cells from immune surveillance is prevented by immune checkpoint inhibitors, allowing the patient's own immune system to attack their cancer. Immune checkpoint inhibitors have shown improvement in overall survival for melanoma, lung cancer and renal cell carcinoma in clinical trials. Unfortunately, not all patients respond to this therapy.In...
National audit on the appropriateness of CT and MRI examinations in LuxembourgAbstractObjectivesIn Luxembourg, the frequency of CT and MRI examinations per inhabitant is among the highest in Europe. A national audit was conducted to evaluate the appropriateness of CT and MRI examinations according to the national referral guidelines for medical imaging.MethodsThree hundred and eighty-eight CT and 330 MRI requests corresponding to already performed examinations were provided by all radiology departments...
Skull base ligamentous mineralisation: evaluation using computed tomography and a review of the clinical relevanceAbstractObjectivesTo determine the frequency, morphologic and demographic characteristics, and clinical relevance of the mineralisation of six skull base ligaments (interclinoid, caroticoclinoid, petrosphenoid, posterior petroclinoid, pterygospinous, and pterygoalar).MethodsThis is a retrospective review of 240 CT scans of the paranasal sinuses (ages 6–80 years). A limited systematic...
An update on Burkitt lymphoma: a review of pathogenesis and multimodality imaging assessment of disease presentation, treatment response, and recurrenceAbstractBurkitt lymphoma (BL) is a highly aggressive, rapidly growing B cell non-Hodgkin lymphoma, which manifests in several subtypes including sporadic, endemic, and immunodeficiency-associated forms. Pathologically, BL is classically characterized by translocations of chromosomes 8 and 14 resulting in upregulation of the c-myc protein transcription...
State of affairs of hybrid imaging in Europe: two multi-national surveys from 2017AbstractObjectivesTo assess the current state of hybrid imaging in Europe with respect to operations, reading and reporting, as well as qualification and training.MethodsThe first survey (LOCAL) was sent to the heads of the departments of radiology and nuclear medicine in Europe in 2017, including 15 questions regarding the organisation of hybrid imaging operations, reporting strategies for PET/CT and the existence...
Role of magnetic resonance imaging in organ-preserving strategies for the management of patients with rectal cancerAbstractTotal mesorectal excision has been the most effective treatment strategy adopted to reduce local recurrence rates among patients with rectal cancer. The morbidity associated with this radical surgical procedure led surgeons to challenge the standard therapy particularly when dealing with superficial lesions or good responders after neoadjuvant radiotherapy, to which radical surgery...
ESGAR 2019 Book of AbstractsDW-MRI of the breast: a pictorial reviewAbstractIn the current era of breast imaging, magnetic resonance imaging (MRI) has an important role. To get its specificity better, some supporting or cooperative tools might be needed. The search for new methods continues and non-contrast MRI trials are seen. With the shorter and easier acquisition, no need for contrast material, diffusion-weighted (DW)-MRI could be the best collaborator. This pictorial review aims to give an overview...
MRI imaging of soft tissue tumours of the foot and ankleAbstractThe majority of soft tissue lesions in the foot and ankle are benign. The aim of this review is to provide the reader with a comprehensive overview of the magnetic resonance imaging (MRI) characteristics of the most common benign and malignant soft tissue neoplasms which occur around the foot and ankle. This should enable the reader to formulate a reasonable differential diagnosis and, most importantly, to recognise those rare aggressive...
DW-MRI of the breast: a pictorial reviewAbstractIn the current era of breast imaging, magnetic resonance imaging (MRI) has an important role. To get its specificity better, some supporting or cooperative tools might be needed. The search for new methods continues and non-contrast MRI trials are seen. With the shorter and easier acquisition, no need for contrast material, diffusion-weighted (DW)-MRI could be the best collaborator. This pictorial review aims to give an overview of the DW-MRI of the...
Temperature alters the hypothalamic transcription of photoperiod responsive genes in induction of...
Temperature alters the hypothalamic transcription of photoperiod responsive genes in induction of seasonal response in migratory redheaded buntingsPublication date: 1 August 2019Source: Molecular and Cellular Endocrinology, Volume 493Author(s): Amit Kumar Trivedi, Sayantan Sur, Aakansha Sharma, SK Tahajjul Taufique, Neelu Jain Gupta, Vinod KumarAbstractWe investigated the temperature effects on hypothalamic transcription of genes involved in the induction of photoperiodic response in redheaded buntings....
Ubiquitin proteasome system (UPS) activation in the cardiac hypertrophy of hyperthyroidismPublication date: 1 August 2019Source: Molecular and Cellular Endocrinology, Volume 493Author(s): Caroline Antunes Lino, Marilene Demasi, Maria Luiza Barreto-ChavesAbstractUbiquitin proteasome system (UPS) is the main proteolytic pathway in eukaryotic cells. Changes in proteasome expression and activity have been associated to cardiovascular diseases as cardiac hypertrophy. Considering that cardiac hypertrophy...
Ubiquitin proteasome system (UPS) activation in the cardiac hypertrophy of hyperthyroidismCaroline Antunes Lino, Marilene Demasi, Maria Luiza Barreto-ChavesArticle 110451Purchase PDFArticle previewAbstractAbstractUbiquitin proteasome system (UPS) is the main proteolytic pathway in eukaryotic cells. Changes in proteasome expression and activity have been associated to cardiovascular diseases as cardiac hypertrophy. Considering that cardiac hypertrophy is commonly associated to hyperthyroidism condition,...
Temperature alters the hypothalamic transcription of photoperiod responsive genes in induction of seasonal response in migratory redheaded buntingsAmit Kumar Trivedi, Sayantan Sur, Aakansha Sharma, SK Tahajjul Taufique, ... Vinod KumarArticle 110454Purchase PDFArticle previewAbstractAbstractWe investigated the temperature effects on hypothalamic transcription of genes involved in the induction of photoperiodic response in redheaded buntings. Birds were exposed at 22 and 38 °C to 13-h long photoperiods...
Role of adiponectin/peroxisome proliferator-activated receptor alpha signaling in human chorionic gonadotropin-induced estradiol synthesis in human luteinized granulosa cellsTao Tao, Yuying Wang, Bing Xu, Xiuying Mao, ... Wei LiuArticle 110450Purchase PDFArticle previewAbstractAbstractImpaired steroid production in polycystic ovary syndrome (PCOS) may result from adiponectin system dysfunction. However, adiponectin's role in ovulatory dysfunction remains unclear. We aimed to determine whether human...
Long non-coding RNA LINC01207 silencing suppresses AGR2 expression to facilitate autophagy and apoptosis of pancreatic cancer cells by sponging miR-143-5pChang Liu, Jin-Ou Wang, Wen-Yang Zhou, Xiao-Ying Chang, ... Xiang-Hong YangArticle 110424Purchase PDFArticle previewAbstractAbstractPancreatic cancer is a serious malignancy accompanied by a well-documented poor prognosis. Accumulating studies have indicated the crucial roles played by long non-coding RNAs (lncRNAs) in proliferation, apoptosis and...
Characterization and differentiation of CD51+ Stem Leydig cells in adult mouse testesPanpan Chen, Xiaoju Guan, Xingxing Zhao, Fenfen Chen, ... Haolin ChenArticle 110449Purchase PDFArticle previewAbstractAbstractIt was reported previously that adult mouse stem Leydig cells (SLCs) express CD51 (integrin α-chain V). However, it is still unclear whether all CD51+ cells are SLCs. In the present study, we found that CD51+ cells can be classified into two sub-groups, a weakly-staining group (CD51+) and...
Steroid receptor/coactivator binding inhibitors: An updateKornelia J. Skowron, Kenneth Booker, Changfeng Cheng, Simone Creed, ... Terry W. MooreArticle 110471Purchase PDFArticle previewAbstractAbstractThe purpose of this review is to highlight recent developments in small molecules and peptides that block the binding of coactivators to steroid receptors. These coactivator binding inhibitors bind at the coregulator binding groove, also known as Activation Function-2, rather than at the ligand-binding...
Targeting Nuclear Receptors with PROTAC degradersJohn J. Flanagan, Taavi K. NeklesaArticle 110452Purchase PDFArticle previewAbstractAbstractNuclear receptors comprise a class of intracellular transcription factors whose major role is to act as sensors of various stimuli and to convert the external signal into a transcriptional output. Nuclear receptors (NRs) achieve this by possessing a ligand binding domain, which can bind cell permeable agonists, a DNA-binding domain, which binds the upstream sequences...
Alternative ligands for thyroid hormone receptorsIván Lazcano, Gabriela Hernández-Puga, Juan Pablo Robles, Aurea OrozcoArticle 110448Purchase PDFArticle previewAbstractAbstractThyroid hormone receptors (TRs) are ligand-dependent transcription factors that activate or repress gene transcription, resulting in the regulation of numerous physiological programs. While 3,3',5-L-triiodothyronine is the TR cognate ligand, these receptors can also be activated by various alternative ligands, including endogenous...
Glutamine deprivation induces metabolic adaptations associated with beta cell dysfunction and exacerbate lipotoxicityRodrigo Carlessi, Jordan Rowlands, Gaewyn Ellison, Heloisa Helena de Oliveira Alves, ... Cyril MamotteIn Press, Corrected Proof, Available online 21 April 2019Purchase PDFArticle previewAbstractAbstractStudies have reported that plasma glutamine is reduced in type 2 diabetes (T2D) patients. Glutamine supplementation improves glycaemic control, however the mechanisms are unclear. Here,...
Alternative retinoid X receptor (RXR) ligandsWojciech Krężel, Ralph Rühl, Angel R. de LeraIn Press, Corrected Proof, Available online 23 April 2019Purchase PDFArticle previewAbstractAbstractRetinoid X receptors (RXRs) control a wide variety of functions by virtue of their dimerization with other nuclear hormone receptors (NRs), contributing thereby to activities of different signaling pathways. We review known RXR ligands as transcriptional modulators of specific RXR-dimers and the associated biological...
7TM proteins are not necessarily GPCRsIeva Vasiliauskaité-Brooks, Robert D. Healey, Sébastien GranierIn Press, Corrected Proof, Available online 24 April 2019Purchase PDFArticle previewAbstractAbstractIn this review article, we summarize the current knowledge on a large and diverse superfamily of seven-pass transmembrane proteins functionally independent from the GPCR superfamily. We include the newest research findings about their physiological roles and their mechanism of action. In particular,...
Relationships between eating disorder psychopathology, sexual hormones and sexual behavioursGiovanni Castellini, Lorenzo Lelli, Emanuele Cassioli, Valdo RiccaIn Press, Corrected Proof, Available online 24 April 2019Purchase PDFArticle previewAbstractAbstractA growing body of evidences demonstrated that sexuality is an important topic in the clinical research of eating disorders (EDs), due to its association with specific psychopathological features, and etiological factors. The present review took...
Effect of neonatal exposure to endosulfan on myometrial adaptation during early pregnancy and labor in ratsRamiro Alarcón, Jorgelina Varayoud, Enrique H. Luque, María M. MilesiIn Press, Corrected Proof, Available online 25 April 2019Purchase PDFArticle previewAbstractAbstractProper myometrial adaptation during gestation is crucial for embryo implantation, pregnancy maintenance and parturition. Previously, we reported that neonatal exposure to endosulfan alters uterine development and induces implantation...
Fish as models for understanding the vertebrate endocrine regulation of feeding and weightHelene VolkoffIn Press, Corrected Proof, Available online 2 May 2019Purchase PDFArticle previewAbstractAbstractThe frequencies of eating disorders and obesity have increased worldwide in recent years. Their pathophysiologies are still unclear, but recent evidence suggests that they might be related to changes in endocrine and neural factors that regulate feeding and energy homeostasis. In order to develop efficient...
Role of regulatory T cells in Schistosoma-mediated protection against type 1 diabetesChun-lian Tang, Yan-ru Gao, Li-xia Wang, Ya-wen Zhu, ... Ying XiongIn Press, Corrected Proof, Available online 9 May 2019Purchase PDFArticle previewAbstractAbstractThe prevalence of T1D in developed societies is partly based on the hygiene hypothesis, that is, the loss of exposure to infectious agents accompanies the loss of immune stimuli shaping the immune system during development. Indeed, the components of parasites,...
Estradiol stimulates adipogenesis and Slc2a4/GLUT4 expression via ESR1-mediated activation of CEBPALuciana A. Fatima, Raquel S. Campello, João N. Barreto-Andrade, Marisa Passarelli, ... Ubiratan F. MachadoIn Press, Corrected Proof, Available online 14 May 2019Purchase PDFArticle previewAbstractGraphical abstractAbstractThe ability of adipose tissue to expand is dependent on adipocyte differentiation and adipose tissue glucose disposal. The CCAAT/enhancer-binding protein alpha (CEBPA) enhances the...
Associations between neuropsychological performance and appetite-regulating hormones in anorexia nervosa and healthy controls: Ghrelin's putative role as a mediator of decision-makingGeorgios Paslakis, Zaida Agüera, Roser Granero, Isabel Sánchez, ... Fernando Fernández-ArandaIn Press, Corrected Proof, Available online 20 May 2019Purchase PDFArticle previewAbstractAbstractAnorexia nervosa (AN) is a severe eating disorder accompanied by alterations in endocrinological circuits and deficits in neuropsychological...
Identification and functional characterization of microRNAs in rat Leydig cells during development from the progenitor to the adult stageHongxia Chen, Xiaoping Guo, Xue Xiao, Leping Ye, ... Zhijian SuIn Press, Accepted Manuscript, Available online 23 May 2019Purchase PDFArticle previewAbstractAbstractThe aim of the present study was to identify microRNAs (miRNAs) that regulate the proliferation and differentiation of Leydig cells (LCs) of rat. Three small RNA libraries derived from progenitor LCs...
FOXE1 inhibits cell proliferation, migration and invasion of papillary thyroid cancer by regulating PDGFAZheng Ding, Ronghu Ke, Yong Zhang, Youben Fan, Jianxia FanIn Press, Accepted Manuscript, Available online 23 May 2019Purchase PDFArticle previewAbstractAbstractPurposeForkhead box E1 (FOXE1) plays an important role in the development, proliferation and differentiation of thyroid cells. However, the biological functions of FOXE1 in papillary thyroid cancer (PTC) remain unclear.Materials and methodsIn...
Correlation between renin-angiotensin system (RAS) related genes, type 2 diabetes, and cancer: Insights from metanalysis of transcriptomics dataLuciana Xavier Pereira, Laryssa Cristina Alves da Silva, Alexya de Oliveira Feitosa, Ricardo Jansen Santos Ferreira, ... Carlos Alberto de Carvalho FragaIn Press, Accepted Manuscript, Available online 28 May 2019Purchase PDFArticle previewAbstractAbstractAlthough studies have provided significant evidence about the role of RAS in mediating cancer risk in...
Defective endoplasmic reticulum export causes proinsulin misfolding in pancreatic β cellsRuimin Zhu, Xin Li, Jialu Xu, Cesar Barrabi, ... Ming LiuIn Press, Accepted Manuscript, Available online 31 May 2019Purchase PDFArticle previewAbstractAbstractEndoplasmic reticulum (ER) homeostasis is essential for cell function. Increasing evidence indicates that, efficient protein ER export is important for ER homeostasis. However, the consequence of impaired ER export remains largely unknown. Herein, we found...
Studying GPCR conformational dynamics by single molecule fluorescenceRobert B. Quast, Emmanuel MargeatIn Press, Accepted Manuscript, Available online 1 June 2019Purchase PDFArticle previewAbstractGraphical abstractAbstractOver the last decades, G protein coupled receptors (GPCRs) have experienced a tremendous amount of attention, which has led to a boost of structural and pharmacological insights on this large membrane protein superfamily involved in various essential physiological functions. Recently,...
The development of the serotonergic and dopaminergic systems during chicken mid-late embryogenesisXiaohong Huang, Shihuan Kuang, Todd J. Applegate, Tsang-long Lin, Heng-wei ChengIn Press, Accepted Manuscript, Available online 2 June 2019Purchase PDFArticle previewAbstractGraphical abstractAbstractSerotonin (5-HT) acts as a morphogen influencing embryonic brain development, and as a neurotransmitter regulating multiple biological functions with lifelong effects on animal physical, physiological and...
Editorial for Special Issue on "Alternative Nuclear Receptor Ligands"Terry W. Moore, Jonna FrasorIn Press, Accepted Manuscript, Available online 4 June 2019Purchase PDF
Altered miR-186 and miR-135a contribute to granulosa cell dysfunction by targeting ESR2: A possible role in polycystic ovary syndromeYuxia Song, Guo Yu, Yungai Xiang, Yan Li, ... Li TanIn Press, Accepted Manuscript, Available online 5 June 2019Purchase PDFArticle previewAbstractAbstractMicroRNAs (miRNAs) are a group of negative regulators of gene expression that function at the posttranscriptional level. Dysregulation of miRNAs is involved in many pathophysiological processes, including polycystic...
Adiponectin is required for pioglitazone-induced improvements in hepatic steatosis in mice fed a high-fat dietMariana de Mendonça, Bruna de Araújo Cardoso dos Santos, Érica de Sousa, Alice Cristina RodriguesIn Press, Accepted Manuscript, Available online 6 June 2019Purchase PDFArticle previewAbstractGraphical abstractAbstractPioglitazone has been used for the treatment of nonalcoholic fatty liver disease (NAFLD) related to diabetes. The role of adiponectin in pioglitazone-induced improvements in...
Introducing article numbering to Molecular and Cellular EndocrinologyIn Press, Corrected Proof, Available online 6 June 2019Download PDF
ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cellsChang Liu, Hsun-Ming Chang, Yuyin Yi, Ying Fang, ... Xiaokui YangIn Press, Accepted Manuscript, Available online 8 June 2019Purchase PDFArticle previewAbstractAbstractAs one of the members of the transforming growth factor-β (TGF-β) superfamily, activin A plays an important role in regulating follicular development and oocyte maturation. Pentraxin 3 (PTX3) is the key component that promotes...
Ubiquitin proteasome system (UPS) activation in the cardiac hypertrophy of hyperthyroidismPublication date: 1 August 2019Source: Molecular and Cellular Endocrinology, Volume 493Author(s): Caroline Antunes Lino, Marilene Demasi, Maria Luiza Barreto-ChavesAbstractUbiquitin proteasome system (UPS) is the main proteolytic pathway in eukaryotic cells. Changes in proteasome expression and activity have been associated to cardiovascular diseases as cardiac hypertrophy. Considering that cardiac hypertrophy...
CorrespondenceNo accessConceptual interpretation of findings on systematic review and meta-analysis of altered-fractionation radiotherapy improves local control in the early-stage glottic carcinomaRama Jayaraj, Chellan Kumarasamy, Shanthi Sabarimurugan, Madurantakam Royam Madhav, ... Siddhartha BaxiIn Press, Corrected Proof, Available online 7 June 2019Purchase PDFselect article Together consideration of microenvironment and tumor cells: Analysis of papers published in Oral OncologyCorrespondenceNo...
Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480
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