GSE101781 The antitumor effect of Batf2 through IL-12 p40 upregulation in tumor-associated macrophages

GSE101781 The antitumor effect of Batf2 through IL-12 p40 upregulation in tumor-associated macrophages: Contributors : Hisashi Kanemaru ; Shizuo Akira

Series Type : Expression profiling by array

Organism : Mus musculus

We assessed the role of basic leucine zipper transcription factor ATF-like 2 (Batf2), particularly its positive transcriptional activities via TLR signals.
Because TLR7 agonists are clinically used against tumors and have proven effective as antitumor drugs, we assessed effect of Batf2 on the responses to the TLR7 ligand (R848).

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