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Publication date: March 2017
Source:International Journal of Psychophysiology, Volume 113





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Publication date: March 2017
Source:International Journal of Psychophysiology, Volume 113





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Publication date: March 2017
Source:International Journal of Psychophysiology, Volume 113





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Correlation between auditory brainstem response and hearing prognosis in idiopathic sudden sensorineural hearing loss patients

Publication date: Available online 31 January 2017
Source:Auris Nasus Larynx
Author(s): Hung-Che Lin, Yu-Ching Chou, Chih-Hung Wang, Li-Wen Hung, Cheng-Ping Shih, Bor-Hwang Kang, Wen-Ying Yeh, Hsin-Chien Chen
ObjectiveTo investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).MethodsPatients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed.ResultsOne hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group.ConclusionsThere was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.



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Correlation between auditory brainstem response and hearing prognosis in idiopathic sudden sensorineural hearing loss patients

Publication date: Available online 31 January 2017
Source:Auris Nasus Larynx
Author(s): Hung-Che Lin, Yu-Ching Chou, Chih-Hung Wang, Li-Wen Hung, Cheng-Ping Shih, Bor-Hwang Kang, Wen-Ying Yeh, Hsin-Chien Chen
ObjectiveTo investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).MethodsPatients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed.ResultsOne hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group.ConclusionsThere was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.



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Biocompatibility of polymer-infiltrated-ceramic-network (PICN) materials with Human Gingival Keratinocytes (HGKs)

Publication date: Available online 31 January 2017
Source:Dental Materials
Author(s): Charlotte Grenade, Marie-Claire De Pauw-Gillet, Catherine Pirard, Virginie Bertrand, Corinne Charlier, Alain Vanheusden, Amélie Mainjot
ObjectiveBiocompatibility of polymer-infiltrated-ceramic-network (PICN) materials, a new class of CAD–CAM composites, is poorly explored in the literature, in particular, no data are available regarding Human Gingival Keratinocytes (HGK). The first objective of this study was to evaluate the in vitro biocompatibility of PICNs with HGKs in comparison with other materials typically used for implant prostheses. The second objective was to correlate results with PICN monomer release and indirect cytotoxicity.MethodsHGK attachment, proliferation and spreading on PICN, grade V titanium (Ti), yttrium zirconia (Zi), lithium disilicate glass-ceramic (eM) and polytetrafluoroethylene (negative control) discs were evaluated using a specific insert-based culture system. For PICN and eM samples, monomer release in the culture medium was quantified by high performance liquid chromatography and indirect cytotoxicity tests were performed.ResultsTi and Zi exhibited the best results regarding HGK viability, number and coverage. eM showed inferior results while PICN showed statistically similar results to eM but also to Ti regarding cell number and to Ti and Zi regarding cell viability. No monomer release from PICN discs was found, nor indirect cytotoxicity, as for eM.SignificanceThe results confirmed the excellent behavior of Ti and Zi with gingival cells. Even if polymer based, PICN materials exhibited intermediate results between Ti–Zi and eM. These promising results could notably be explained by PICN high temperature–high pressure (HT–HP) innovative polymerization mode, as confirmed by the absence of monomer release and indirect cytotoxicity.

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Correlation between auditory brainstem response and hearing prognosis in idiopathic sudden sensorineural hearing loss patients

Publication date: Available online 31 January 2017
Source:Auris Nasus Larynx
Author(s): Hung-Che Lin, Yu-Ching Chou, Chih-Hung Wang, Li-Wen Hung, Cheng-Ping Shih, Bor-Hwang Kang, Wen-Ying Yeh, Hsin-Chien Chen
ObjectiveTo investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).MethodsPatients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed.ResultsOne hundred and two patients (54 men and 48 women) were included in the study. Hearing recovery was observed in 72 cases (70.6%). Waves I, III, and V latencies were significantly prolonged in the affected ears compared with the unaffected ears. A smaller wave I amplitude was found in the affected ear compared with the unaffected ear in the three recovery groups. There was a significant association between wave I latency and hearing outcome (p=0.009) with a prolonged trend from complete to slight hearing recovery group.ConclusionsThere was a significant correlation between wave I latency and hearing outcome in patients with ISSNHL. The finding may provide diagnostic information and serve as a potential prognostic indicator in patients with ISSNHL.



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