3-O-Laurylglyceryl ascorbate reinforces skin barrier function

 through not only the reduction of oxidative stress but also the activation of ceramide synthesis:

Abstract

AsA (ascorbic acid), GSH (glutathione), HBSS (Hanks balanced salt solution), HPTLC (high performance thin layer chromatography), IL (interleukin), MAP (magnesium ascorbyl phosphate), NHEKs (normal human epidermal keratinocytes), Nrf2 (nuclear factor E2-related factor 2), PBS (phosphate buffered saline), PPAR (peroxisome proliferator activated receptor), RHEEs (reconstructed human epidermis equivalents), ROS (reactive oxygen species), SC (stratum corneum), SPT (serine palmitoyltransferase), TEWL (trans-epidermal water loss), VC-3LG (3-O-laurylglyceryl ascorbate)

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