Immunohistochemistry as a Practical Tool in Molecular Pathology.

Immunohistochemistry as a Practical Tool in Molecular Pathology.

Arch Pathol Lab Med. 2016 Aug;140(8):766-769

Authors: Sheffield BS

Abstract
CONTEXT: -Molecular genetics is playing an increasingly important role in patient care and pathology practice. Immunohistochemistry (IHC) is a valuable and practical tool employed by most pathologists on a regular basis.
OBJECTIVE: -To highlight select examples of how IHC may be used in the realm of molecular diagnostics.
DATA SOURCES: -Select sources on IHC relating to tumor subtyping, hereditary cancer screening, and treatment-response prediction are reviewed. These represent some of the areas in which IHC can be employed by anatomic pathologists to optimize patient care and further inform molecular testing.
CONCLUSION: -In the emerging era of personalized medicine, IHC continues to serve a valuable function, complementing and enhancing other molecular techniques.

PMID: 27472235 [PubMed - as supplied by publisher]

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