The role of platelets in atherosclerotic process and subsequently in the pathophysiology of cardiovascular disease is essential as platelets in addition to their contribution to thrombosis and hemostasis modulating inflammatory reactions and immune response. Platelets after adhesion on the injured vascular endothelium and activation release a wide range of molecules stored in platelets granules such as chemokines, proinflammatory molecules and other biological response modulators accelerating interaction among platelets, endothelial cells and leukocytes. These interactions establish a localized inflammatory response that promotes the atherosclerotic process. Moreover, activated platelets give rise to microparticles another active participant within the blood stream. The purpose of this review is to present the role of platelets in the above mechanisms giving an emphasis on the nature of the platelet derived- molecules and their contribution to the atherosclerotic process.
http://ift.tt/2cdwNjv
http://ift.tt/2bReRtV
Ιατρική : Τα αισθητικά συστήματα της όρασης,ακοής,αφής,γεύσης και όσφρησης.
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Publication date: April 2017 Source: European Journal of Vascular and Endovascular Surgery, Volume 53, Issue 4 http://ift.tt/2oUTFL8 ...
-
Publication date: Available online 8 April 2017 Source: European Journal of Vascular and Endovascular Surgery Author(s): M. Venermo, K. Ma...
-
Related Articles Identification of somatic TERT promoter mutations in familial non-medullary thyroid carcinomas (FNMTC). Clin Endocri...
-
Correlation Between the Epworth Sleepiness Scale and the Maintenance of Wakefulness Test in Patients With Narcolepsy Participating in Two Cl...
-
AbstractBackground Little is known about patterns of medication use and lifestyle counseling in patients with peripheral artery disease (PA...
-
Stereotact Funct Neurosurg 2017;95:69 http://ift.tt/2lpc3FI http://ift.tt/2mcIz2i
-
# Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174, alsfakia@gmail.com , T...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου