Fertility preservation in women with CNS tumors.

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Fertility preservation in women with CNS tumors.

Expert Rev Anticancer Ther. 2017 Apr 11;:

Authors: Tosoni A, Balestrini D, Brandes AA

Abstract
INTRODUCTION: Fertility impairment due to treatments is a major concern for adolescents and young adult patients who survived cancer. Areas covered: Chemotherapy may determine a detrimental effect on ovary function, leading to infertility, and premature ovarian failure. Embryo and oocyte cryopreservation is a standard strategy for fertility preservation; other strategies, such as gonadal tissue cryopreservation and the use of gonadotropin -releasing hormone agonist, are still considered experimental. There are few data available regarding the effect of pregnancy on glioma, which indicates tumor progression during pregnancy in 33-45% of patients. Expert commentary: Glioma patients need to be advised about the risk of tumor progression during pregnancy, and about the possible, even if not proven, interaction between hormone stimulation and tumor growth.

PMID: 28395560 [PubMed - as supplied by publisher]

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