PARAMEDIC SUPPLIED "TAKE HOME" NALOXONE: A RANDOMISED FEASIBILITY STUDY: Introduction
"Take Home" Naloxone (THN) kits for use in the event of an opioid overdose may reduce further overdose and deaths, but distribution through Drugs Services may not reach those at highest risk. Attendance by paramedics at emergency calls for opioid overdose presents an opportunity to distribute THN kits. This feasibility study will assess the acceptability of THN, and gather data to inform definitive trial planning.
Methods and analysis
Cluster randomised trial with staggered allocation of paramedics (clusters) to groups. Paramedics in an urban area of south Wales, UK were invited to take part and randomly allocated to training. Patients attended by trained paramedics and issued THN kits fell into the intervention group. Patients attended by paramedics following usual practice (until they received their training) fell into the control group. We will gather data about processes and outcomes of care: numbers of patients eligible for intervention, offered and accepted THN, attended Emergency Department, suffered further overdose, died within 12 months; and about follow up rates: numbers of patients consented, completed questionnaire (postal or telephone). We will gather qualitative data about acceptability to patients and paramedics through interviews and focus groups.
Preliminary findings (unvalidated data)
85 of 102 eligible paramedics took part. The number of opioid related EMS contacts (n=215), exceeded the number predicted (100–120) for the 12-months period. Of the 182 cases attended by study paramedics, 148 were attended by trained paramedics. 35 of the 55 patients eligible for the intervention were offered it. 25 accepted the intervention, received training and a THN kit. As anticipated, follow-up of participants proved challenging. Of the 215 events for which we have data, 58 were repeat episodes involving 25 individual users. The number of repeat encounters experienced by these individuals ranged from 2 to 5. Six deaths were recorded during the study period.
http://ift.tt/2cslsfR
Ιατρική : Τα αισθητικά συστήματα της όρασης,ακοής,αφής,γεύσης και όσφρησης.
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Evaluation of the effect of three mouthwashes on the mechanical properties and surface morphology of several orthodontic wires: An in vitro ...
-
Thyroid hormone level is associated with the frequency and severity of acute transverse myelitis. : Acute transverse myelitis (ATM) is a pro...
-
Abstract Background Drug-related problems are mostly preventable or predictable circumstances that may impact on health outcomes. Clinica...
-
Alternative Techniques in Özgür Sürmelioğlu 1 , Süleyman Özdemir 1 , Özgür Tarkan 1 , Ülkü Tuncer 1 , Fikret Çet...
-
Cancers, Vol. 9, Pages 92: Regional Delivery of Chimeric Antigen Receptor (CAR) T-Cells for Cancer Therapy : Cancers, Vol. 9, Pages 92: Re...
-
Abstract Objectives The aim of this systematic review was to determine whether soft tissue biotype at implant placement has an influenc...
-
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182, A case of occult bilateral optic nerve...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου