Σάββατο 31 Δεκεμβρίου 2016

IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis

Current treatments for generalized pustular psoriasis are unsatisfactory. We applied recently-developed techniques for transcriptomic analysis of archived FFPE biopsies revealing pro-inflammatory IL-1, IL-17, TNF and IL-36 activity, which provides a rationale for biologic targeting of these cytokines.

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