Τρίτη 6 Δεκεμβρίου 2016

Low Concentration PM10 Had No Effect on Nasal Symptoms and Flow in Allergic Rhinitis Patients.

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Low Concentration PM10 Had No Effect on Nasal Symptoms and Flow in Allergic Rhinitis Patients.

Clin Exp Otorhinolaryngol. 2016 Dec 02;:

Authors: Kim YH, Ko KP, Kang IG, Jung JH, Oh DK, Jang TY, Kim ST

Abstract
Objectives: Since Korea is geographically close to China (the origin site for Asian sand dust [ASD]) the health influence of ASD event will be still greater in Korea. We aimed to evaluate the effect of PM10 (particulate matter with aerodynamic diameter <10 μm, below 150 μg/m3) on the clinical course of allergic rhinitis (AR).
Methods: We enrolled 47 healthy volunteers (group A) and 108 AR patients sensitized to house dust mites (group B). For 120 consecutive days (from February 1st to May 30th, 2012), all subjects reported their daily nasal symptoms and performed 2 peak flowmeter readings to measure peak nasal inspiratory flow (PNIF). We evaluated the correlation between the daily concentration of PM10, symptoms, and PNIF. of patients. We also investigated changes in symptoms and PNIF 2 days before and after 'dusty' days (daily concentration of PM10 >100 μg/m3).
Results: There was no significant difference between group A and B in nasal symptoms and PNIF during the 120-day period. Changes in nasal symptoms and PNIF were not statistically significant before or after a PM10 concentration rise above 100 μg/m3.
Conclusion: Low concentration PM10 does not have significant effect on nasal symptoms and PNIF in AR patients.

PMID: 27903069 [PubMed - as supplied by publisher]



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