Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging.

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Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging.

Chem Commun (Camb). 2018 Mar 28;:

Authors: A AH, Sreedharan S, Ali F, Smythe CG, Thomas JA, Das A

Abstract
A new physiologically benign and cell membrane permeable BODIPY based molecular probe, MB-Sn, specifically senses intracellular hydrogen polysulfides (H2Sn, n > 1) localized in the endoplasmic reticulum. This reagent is suitable for mapping the intracellular distribution of H2Sn by wide-field as well as super-resolution Structured Illumination Microscopy (SIM).

PMID: 29589001 [PubMed - as supplied by publisher]

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