Cancer

 American Journal of Clinical Oncology - Published Ahead-of-Print

Atypical Lipomatous Tumors: Does Our Inconsistent Terminology Have Patient Repercussions? Results of a Meta-Analysis

Objectives: Misnaming low-grade lipomatous tumors poses a clinical and medicolegal challenge, potentially subjecting patients to expensive and unnecessary surgeries. The terms atypical lipomatous tumor (ALT) and "well-differentiated" liposarcoma (WDL) have been used interchangeably in pathology reports, scholarly works and consensus recommendations, creating vagaries between low-virulence extremity tumors and retroperitoneal disease with metastatic potential. Methods: A systematic review...

American Journal of Clinical Oncology - Published Ahead-of-Print

Fri Mar 29, 2019 02:00

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 Anti-Cancer Drugs - Published Ahead-of-Print

A novel thiosemicarbazone as a promising effective and selective compound for acute leukemia

Acute leukemias are a heterogeneous group of aggressive malignant neoplasms associated with severe morbidities due to the nonselectivity of current chemotherapeutic drugs to nonmalignant cells. The investigation of novel natural and synthetic structures that might be used for the development of new drugs with greater efficiency and selectivity to leukemic cells is mandatory. In this context, thiosemicarbazones have been well described in the literature by their several biological properties and their...

Anti-Cancer Drugs - Published Ahead-of-Print

Fri Mar 29, 2019 02:00

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 BMC Cancer - Latest Articles

NUP98 – a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer

Triple Negative breast cancer (TNBC) is a poor outcome subgroup of breast cancer defined based on the absence of expression of ERα and PR and HER2 amplification. These hard to treat cancers lack targeted treat...

BMC Cancer - Latest Articles

Tue Apr 02, 2019 03:00

LncRNA ENST00000539653 acts as an oncogenic factor via MAPK signalling in papillary thyroid cancer

Papillary thyroid cancer (PTC) is the most frequent type of thyroid malignancy. In this study, we investigated the mechanisms whereby long non-coding RNAs (lncRNAs) are associated with PTC pathogenesis.

BMC Cancer - Latest Articles

Tue Apr 02, 2019 03:00

Early assessment with 18F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography to predict short-term outcome in clear cell renal carcinoma treated with nivolumab

We reported previously the usefulness of 18F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to predict prognosis of renal cell carcinoma (RCC) treated with molecular targ...

BMC Cancer - Latest Articles

Tue Apr 02, 2019 03:00

Cytology material is equivalent to tumor tissue in determining mutations of BRCA 1/2 genes in patients with tubo-ovarian high grade serous carcinoma

High-grade serous ovarian cancer is a detrimental disease. Treatment options in patients with a recurrent disease are dependent on BRCA1/2 mutation status since only patients with known BRCA mutation are eligible...

BMC Cancer - Latest Articles

Tue Apr 02, 2019 03:00

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 British Journal of Cancer - AOP

Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer

Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancerHarnessing the innate immune system and local immunological microenvironment to treat colorectal cancer, Published online: 02 April 2019; doi:10.1038/s41416-019-0441-6Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer

British Journal of Cancer - AOP

Tue Apr 02, 2019 02:57

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