Plasmablastic lymphoma: oral presentation in patient suffering from osteradionecrosis of the jaw.

Plasmablastic lymphoma: oral presentation in patient suffering from osteradionecrosis of the jaw.

Int J Surg Case Rep. 2016 Nov 3;29:94-97

Authors: Kichenbrand C, Egloff C, Guillet J, Delaître B, Bastien C, Leroux A, Dolivet G, Phulpin B

Abstract
INTRODUCTION: We describe here an unusual presentation of a plasmablastic lymphoma in a patient suffering from an osteoradionecrosis of the jaw.
PRESENTATION OF CASE: We report the case of a 64-year-old patient who was followed up on oncology because of an oropharyngeal cancer treated by a combined procedure of both surgery and radio-chemotherapy procedure. This patient developed an osteoradionecrosis of the jaw. In the vicinity of this necrotic area appeared an ulceration which could evoke a new necrotic area. Given the persistence of this ulceration, a biopsy was performed which highlighted a plasmablastic lymphoma oral localization.
DISCUSSION: The plasmablastic lymphoma, belonging to the diffuse large B-cell lymphoma family, is a very aggressive and unusual form of cancer with poor prognosis. If it is found mainly in patients with positive HIV, in whom it was first described, it is also found in immunosuppressed patients such as transplanted patients or patients suffering from leukaemia.
CONCLUSION: Plasmablastic lymphoma is a rare and an aggressive pathology in immunocompetent patients.

PMID: 27837702 [PubMed - as supplied by publisher]

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